Generation of highly proliferative, rejuvenated cytotoxic T cell clones through pluripotency reprogramming for adoptive immunotherapy
Yohei Kawai, Ai Kawana‐Tachikawa, Shuichi Kitayama, Tatsuki Ueda, Shoji Miki, Akira Watanabe, Shin Kaneko
Topics & Concepts
ReprogrammingCytotoxic T cellAdoptive immunotherapyImmunotherapyAdoptive cell transferBiologyCancer researchCancer immunotherapyImmunologyCell biologyCellGeneticsImmune systemIn vitroCAR-T cell therapy researchCRISPR and Genetic EngineeringPluripotent Stem Cells Research