Degradation of Selected Antidepressants Sertraline and Citalopram in Ultrapure Water and Surface Water Using Gamma Radiation
Anna Bojanowska-Czajka, Marta Pyszynska, Agnieszka Majkowska‐Pilip, Kamil Wawrowicz
Abstract
Gamma radiation was applied to degradation selected antidepressants in ultrapure water and surface water. Additionally, the influence of typical radical scavengers like carbonate, nitrate and humic acid was determined. The cytotoxicity towards liver cells HepG2 and colon cells Caco2 were measured during the radiation process. It was found that radiation technology, specifically ionizing radiation, can achieve satisfactory degradation efficiency with both SER and CIT. It was shown that the process of decomposition of the tested antidepressants with the highest efficiency occurs in the reaction with the hydroxyl radical.
Topics & Concepts
Ultrapure waterDegradation (telecommunications)ChemistryIonizing radiationDecompositionHumic acidRadiationNuclear chemistryEnvironmental chemistryMaterials scienceIrradiationOrganic chemistryNanotechnologyPhysicsTelecommunicationsComputer scienceQuantum mechanicsNuclear physicsFertilizerPharmaceutical and Antibiotic Environmental ImpactsRadiation Effects and DosimetryAdvanced oxidation water treatment