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Membrane estrogen receptor ERα activation improves tau clearance via autophagy induction in a tauopathy cell model

Angélica Jardim Costa, Rafaela Brito Oliveira, Patrícia Wachilewski, Michelle Sayuri Nishino, Taysa Bervian Bassani, Roberta Sessa Stilhano, Janete M. Cerutti, Bruno Nozima, Catarina S. Porto, Gustavo J.S. Pereira, Ana López Ramírez, Soraya S. Smaili, Rodrigo Portes Ureshino

2022Brain Research14 citationsDOI

Topics & Concepts

AutophagyTauopathyEstrogen receptorCell biologyNeuroprotectionEstrogenPI3K/AKT/mTOR pathwayBiologyTau proteinChemistryEndocrinologyInternal medicineSignal transductionNeurodegenerationPharmacologyApoptosisBiochemistryAlzheimer's diseaseMedicineDiseaseCancerBreast cancerAlzheimer's disease research and treatmentsAutophagy in Disease and TherapyNeurogenesis and neuroplasticity mechanisms
Membrane estrogen receptor ERα activation improves tau clearance via autophagy induction in a tauopathy cell model | Litcius