Papulo‐purpuric dermatitis of childhood: a distinct PLEVA‐like eruption associated to SARS‐CoV‐2 infection. Clinical, histopathological and immunohistochemical study of 10 cases
Raffaele Gianotti, Lucia Restano, Mario Cutrone, Cristiana Colonna, Giovanni Fellegara, Isacco Debernardi, Francesca Boggio, Alessandro Del Gobbo, Nicola Adriano Monzani, Claudio Tripodo, Carlo Gelmetti, Emilio Berti
Abstract
We observed ten children with a papular eruption with purpuric features during the SARS-CoV-2 pandemic in Northern Italy (May-December 2020). Histological examination showed signs of SARS-CoV-2-related dermatosis. Evidence of nucleocapsid viral proteins using SARS-CoV-2 (2019-nCoV) nucleocapsid antibody revealed cuticular staining of the deep portion of the eccrine glands in all cases.
Topics & Concepts
MedicineDermatologyImmunohistochemistryCoronavirus disease 2019 (COVID-19)PathologyDiseaseInfectious disease (medical specialty)Dermatological and COVID-19 studiesParvovirus B19 Infection StudiesCutaneous lymphoproliferative disorders research