A chitosan-based multifunctional hydrogel containing <i>in situ</i> rapidly bioreduced silver nanoparticles for accelerating infected wound healing
Fengxin Zhao, Yifan Liu, Tao Song, Bin Zhang, Dongxiao Li, Yumei Xiao, Xingdong Zhang
Abstract
results indicated that the COC@AgNP hydrogel accelerated the healing process of infected full-thickness skin defects through anti-infection, anti-inflammation, stimulating collagen deposition, and promoting the formation of epithelia and blood vessels. Collectively, the COC@AgNP hydrogel has good potential for clinical infected wound dressing applications.
Topics & Concepts
ChitosanMaterials scienceIn situNanoparticleWound healingNanotechnologySelf-healingChemical engineeringChemistryMedicineEngineeringSurgeryOrganic chemistryAlternative medicinePathologyWound Healing and TreatmentsElectrospun Nanofibers in Biomedical ApplicationsSilk-based biomaterials and applications