Genomic Insight into the Antimicrobial Resistance of <i>Streptococcus Suis</i> — Six Countries, 2011–2019
Lichao Ma, Wanjiang Zhang, Jingyun Ma, Qingpo Cui, Chaoyang Zhang, Peng Zhang, Chengtao Sun, Huarun Sun, Yao Zhu, Shaolin Wang, Shuangyang Ding, Gongzheng Hu, Zhangqi Shen
Abstract
<abstract abstract-type="Summary"> <sec> <b>What is already known on this topic?</b> <i>Streptococcus suis</i> (<i>S. suis</i>) is a zoonotic pathogen causing disease in humans and animals, and the emergence of its increased resistance to antimicrobial agents has become a significant challenge in many countries. </sec><sec> <b>What is added by this report?</b> Using whole genome sequencing data to accurately predict antimicrobial resistance determinants, it was found that the prevalence of antimicrobial resistance genes was higher in the pig isolates of <i>S. suis</i> than in the human isolates and that the prevalence of these genes varied with serotype. </sec><sec> <b>What are the implications for public health practice?</b> The data regarding <i>S. suis</i> antimicrobial resistance will help guide rational drug use in the clinic to better protect the health of humans and animals. </sec>