Intratumoral Microbiota-Host Interactions Shape the Variability of Lung Adenocarcinoma and Lung Squamous Cell Carcinoma in Recurrence and Metastasis
Xiangfeng Zhou, Lei Ji, Yanyu Ma, Geng Tian, Kebo Lv, Jialiang Yang
Abstract
Our study elucidates significant differences in RM-associated host-microbe interactions between LUAD and LUSC. Besides, the microbes in tumor tissue could be used to predict the RM risk of LUSC, and the predicted risk score is associated with patients' survival.
Topics & Concepts
AdenocarcinomaMetastasisLungBasal cellSquamous carcinomaLung cancerCarcinomaBiologyOncologyMedicinePathologyInternal medicineCancer researchCancerLung Cancer Diagnosis and TreatmentRadiomics and Machine Learning in Medical Imaging