Inhibiting the Piezo1 channel protects microglia from acute hyperglycaemia damage through the JNK1 and mTOR signalling pathways
Hailin Liu, Wengong Bian, Dongxia Yang, Mingmin Yang, Heguo Luo
Topics & Concepts
MicrogliaPIEZO1PI3K/AKT/mTOR pathwayDownregulation and upregulationCell biologyChemistryMedicineInternal medicineInflammationSignal transductionBiologyIon channelReceptorBiochemistryGeneMechanosensitive channelsErythrocyte Function and PathophysiologyHydrogen's biological and therapeutic effectsNeutrophil, Myeloperoxidase and Oxidative Mechanisms