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Structure of GPR101–Gs enables identification of ligands with rejuvenating potential

Yang Zhao, Junyan Wang, Fan Yang, Kongkai Zhu, Guopeng Wang, Ying Guan, Shanglei Ning, Yan Lü, Yu Li, Chao Zhang, Yuan Zheng, Shuhua Zhou, Xinwen Wang, Ming‐Wei Wang, Peng Xiao, Fan Yi, Cheng Zhang, Pengju Zhang, Fei Xu, Baohua Liu, Hua Zhang, Xiao Yu, Ning Gao, Jin‐Peng Sun

2023Nature Chemical Biology26 citationsDOI

Topics & Concepts

In silicoMutantCell biologyReceptorChemistryG protein-coupled receptorComputational biologyOrphan receptorBiologySignal transductionBiophysicsBiochemistryTranscription factorGeneReceptor Mechanisms and SignalingIon Transport and Channel RegulationProtein Kinase Regulation and GTPase Signaling
Structure of GPR101–Gs enables identification of ligands with rejuvenating potential | Litcius