Optimized design of obstacle sequences for microfluidic mixing in an inertial regime
Matteo Antognoli, Daniel Stoecklein, Chiara Galletti, Elisabetta Brunazzi, Dino Di Carlo
Abstract
)), observing fluid flow shape and mixing index at several cross-sections, reaching mixing efficiencies around 80%. Furthermore, we investigated the effect of the inter-pillar spacing on the most optimal design, quantifying the tradeoff between mixing performance and hydraulic resistance. These micromixer designs and the framework for the design in inertial regimes can be used for various applications, such as lipid nanoparticle fabrication which has been of great importance in vaccine scale up during the pandemic.
Topics & Concepts
Mixing (physics)MicromixerMicrofluidicsMechanicsComputational fluid dynamicsFlow (mathematics)ConvectionBiological systemComputer scienceSimulationMechanical engineeringMaterials scienceNanotechnologyPhysicsEngineeringBiologyQuantum mechanicsMicrofluidic and Capillary Electrophoresis ApplicationsMicrofluidic and Bio-sensing TechnologiesInnovative Microfluidic and Catalytic Techniques Innovation