Trisomy 21 results in modest impacts on mitochondrial function and central carbon metabolism
Colin C. Anderson, John Marentette, Kendra M. Prutton, Abhishek K. Rauniyar, Julie A. Reisz, Angelo D’Alessandro, Kenneth N. Maclean, Laura Saba, James R. Roede
Topics & Concepts
MitochondrionOxidative stressBiologyPentose phosphate pathwayGlutamineGlycolysisMitochondrial diseaseMetabolismCell biologyBiochemistryMitochondrial DNAAmino acidGeneDown syndrome and intellectual disability researchFrailty in Older AdultsEpigenetics and DNA Methylation