Novel 1,2,4-triazole derivatives as apoptotic inducers targeting p53: Synthesis and antiproliferative activity
Hesham A. M. Gomaa, Hany A.M. El-Sherief, Shaimaa Hussein, Ahmed M. Gouda, Ola I. A. Salem, Khalid Saad Alharbi, Alaa M. Hayallah, Bahaa G. M. Youssif
Topics & Concepts
ChemistryDoxorubicinApoptosisDocking (animal)In vitroStereochemistryMdm2InducerTriazolePharmacologyBiochemistryChemotherapyInternal medicineNursingOrganic chemistryGeneMedicineClick Chemistry and ApplicationsSynthesis and Characterization of Heterocyclic CompoundsCancer-related Molecular Pathways