Low-dose Esketamine suppresses NLRP3-mediated apoptotic and pyroptotic cell death in microglial cells to ameliorate LPS-induced depression via ablating GSK-3β
Sen Zhou, Yang Liu, Binbin Xue, Pei-Gen Yuan
Topics & Concepts
NeuroinflammationPyroptosisApoptosisProgrammed cell deathPharmacologyInflammasomeMicrogliaMedicineInflammationInternal medicineChemistryBiochemistryTryptophan and brain disordersNeuroinflammation and Neurodegeneration MechanismsStress Responses and Cortisol