Deletion of <i>DP148R</i> , <i>DP71L</i> , and <i>DP96R</i> Attenuates African Swine Fever Virus, and the Mutant Strain Confers Complete Protection against Homologous Challenges in Pigs
Xiaolan Qi, Tao Feng, Zhao Ma, Linlin Zheng, Huanan Liu, Zhengwang Shi, Chaochao Shen, Pan Li, Panxue Wu, Yi Ru, Dan Li, Zixiang Zhu, Hong Tian, Sen Wu, Haixue Zheng
Abstract
Ongoing outbreaks of African swine fever (ASF) have considerably damaged the pig industry in affected countries. Thus, a safe and effective vaccine is important to control African swine fever spread.
Topics & Concepts
BiologyVirologyStrain (injury)MutantHomologous chromosomeAfrican swine fever virusVirusGeneticsGeneAnatomyAnimal Disease Management and EpidemiologyVector-Borne Animal DiseasesT-cell and Retrovirus Studies