Oxygen vacancy boosting Fenton reaction in bone scaffold towards fighting bacterial infection
Cijun Shuai, Xiaoxin Shi, Feng Yang, Haifeng Tian, Pei Feng
Abstract
Highlights High-energy ball milling was proposed to construct oxygen vacancy defects. Scaffold with individualized shape and porous structure was fabricated by selective laser sintering. Antibacterial material was used to adsorb H 2 O 2 to the site of bacterial infection. The accumulated H 2 O 2 could amplify the Fenton reaction efficiency to induce more ·OH. The scaffold possessed matched mechanical properties and good biocompatibility.
Topics & Concepts
BiocompatibilityScaffoldOxygenPorosityBall millMaterials scienceVacancy defectSinteringChemical engineeringChemistryComposite materialBiomedical engineeringOrganic chemistryMetallurgyMedicineEngineeringCrystallographyBone Tissue Engineering MaterialsNanoplatforms for cancer theranosticsAdvanced Photocatalysis Techniques