IL-10 derived from Hepatocarcinoma cells improves human induced regulatory T cells function via JAK1/STAT5 pathway in tumor microenvironment
Shaopeng Zhang, Xiaojie Gan, Jiannan Qiu, Zheng Ju, Ji Gao, Jinren Zhou, Chengyu Shi, Yaqing Zhu, Zhang Li
Topics & Concepts
FOXP3STAT5IL-2 receptorCancer researchImmune systemTumor microenvironmentApoptosisRegulatory T cellAntibodySTAT3ImmunologyChemistryBiologyT cellPhosphorylationCell biologyBiochemistryImmune Cell Function and InteractionT-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers