Restoring NK cells functionality via cytokine activation enhances cetuximab-mediated NK-cell ADCC: A promising therapeutic tool for HCC patients
Shahenda Mahgoub, Hadeer Abosalem, Mohamed Emara, Nahla S. Kotb, A. Maged, Sameh H. Soror
Topics & Concepts
Antibody-dependent cell-mediated cytotoxicityNKG2DCytotoxic T cellInterleukin 12CD16ImmunologyDownregulation and upregulationCancer researchInterleukin 21Natural killer cellImmune systemBiologyAntibodyMonoclonal antibodyT cellCD8In vitroCD3GeneBiochemistryImmune Cell Function and InteractionHematopoietic Stem Cell TransplantationCAR-T cell therapy research