Surviving Sepsis Campaign: international guidelines for management of sepsis and septic shock 2026
Hallie C. Prescott, Massimo Antonelli, Waleed Alhazzanic, Morten Hylander Møller, Fayez Alshamsi, Luciano C. P. Azevedo, E Belley-Cote, Jan De Waele, Lennie Derde, Joanna C. Dionnec, L.E. Evans, Hayley B. Gershengorn, Carol L. Hodgson, Kimia Honarmandc, Jozef Kesecioğlu, Lauralyn McIntyre, Mervyn Mer, Mark Nunnally, Simon Oczkowski, Bram Rochwergc, Olurotimi Akinola, Kwame Akuamoah-Boateng, Laura Alberto, D Angus, Yassen Arabi, E. Azoulay, Maurizio Cecconi, Pauline Convocar, Gennaro De Pascale, Kent Doi, Bin Du, Moritoki Egi, Marie-Carmelle Elie-Turenne, R. Ferrer, Alison Fox-Robichaud, Craig French, Yonathan Freund, Michelle Ng Gong, Caleb P. Hale, Naomi Hammond, Madiha Hashmi, L. Heunks, Theodore J. Iwashyna, Shevin T. Jacob, Michael Klompas, Arthur Kwizera, Murdoch Leeies, Joanna D. Lejnieks, Mitchell M. Levy, Flavia R. Machado, M. D. Maia, Henry Masur, Ryan C. Maves, Steven McGloughlin, J. McPeake, Nicholas M. Mohr, Sheila Nainan Myatra, Marlies Ostermann, S. Peake, M W Pletz, Jay Roberts, Regis G. Rosa, Robert Sawyer, Christa Schorr, Steven Q. Simpson, Li Weng, W. Joost Wiersinga, A Rhodes, Craig M. Coopersmith
Abstract
Sepsis, life-threatening acute organ dysfunction due to infection [ 1 ], is a global health priority [ 2 , 3 ] with approximately 49 million cases and 13 million sepsis-related deaths each year [ 4 , 5 , 6 ]. Beyond being acutely deadly, sepsis contributes to new and worsened physical, cognitive, and mental health problems in many survivors [ 7 , 8 ]. Early identification and treatment are critical to improving outcomes.