Environmental and biomedical applications in the synthesis and structural, optical, elemental characterizations of Mg doped ZnO nanoparticles using Coleus aromaticus leaf extract
S.M. Fathima Khyrun, Z. Mohamed Riyas, V. Raja, Sulthana Sabura Sarbudeen, Vinothini Natesan, K. Velsankar, S. Sudhahar, M. Ramesh Prabhu, Mydhili Govindarasu, Muthu Thiruvengadam, Baskar Venkidasamy, Chandran Janani, Thevasundari Selvaraj
Abstract
Green nanotechnology is critical in the development of novel and successful treatment techniques for wide range of diseases. Biological production of metal nanoparticles has traditionally been recognized as an effective replacement to current chemical methodologies. The green production of Magnesium doped Zinc oxide nanoparticles (Mg-ZnO NPs) was produced using Coleus aromaticus leaves extract. The crystalline structure was observed in the X-ray diffraction pattern, with an approximate crystalline size of 30nm. The metal oxygen bonding in the prepared sample is clearly visible in the FTIR spectrum. The UV-Visible analysis confirms the SPR band at 371nm and the band gap energy is found to be 3.38 eV. The particle size analyzer (DLS) reveals the Mg-ZnO NPs size range between 40-60 nm. The photoluminescence spectrum represented emission peak in the visible region (627 nm). FESEM images portrayed hexagonal and spherical shaped Mg-ZnO NPs. The existence of Mg, Zn, and O revealed the formation of homogeneous Mg-ZnO NPs in the EDAX spectrum and tracing. The antimicrobial assay depicted good toxicity against bacterial and fungal strains. The antioxidant assay expressed potential free radical scavenging compared to the standard ascorbic acid. High anti-diabetic behavior was achieved in anti-diabetic α–glucosidase inhibition assay. Our results revealed that Mg-ZnO NPs produced from C. aromaticus leaf extract might be a safe and efficacious resource of UV protective, anti‒bacterial, and anti‒diabetic compounds.