Cancer therapies based on targeted protein degradation — lessons learned with lenalidomide
Max Jan, Adam S. Sperling, Benjamin L. Ebert
Topics & Concepts
DruggabilityThalidomideMedicineDrug discoveryDrug developmentLenalidomideFulvestrantPomalidomideProtein degradationBioinformaticsPharmacologyCancerDrugCancer researchBiologyMultiple myelomaInternal medicineEstrogen receptorBreast cancerGeneticsCell biologyGeneProtein Degradation and InhibitorsMultiple Myeloma Research and TreatmentsUbiquitin and proteasome pathways