A synergy between the catalytic and structural Zn(II) ions and the enzyme and substrate dynamics underlies the structure–function relationships of matrix metalloproteinase collagenolysis
Ann Varghese, Shobhit S. Chaturvedi, Gregg Fields, Tatyana G. Karabencheva‐Christova
Topics & Concepts
Substrate (aquarium)Matrix metalloproteinaseEnzymeFunction (biology)CatalysisMatrix (chemical analysis)Substrate specificityIonChemistryStructure functionBiophysicsBiological systemBiochemistryBiologyPhysicsCell biologyEcologyParticle physicsOrganic chemistryChromatographyProtease and Inhibitor MechanismsPeptidase Inhibition and AnalysisEnzyme Production and Characterization