OGT regulated O-GlcNacylation promotes migration and invasion by activating IL-6/STAT3 signaling in NSCLC cells
Xin Ge, Xiao Peng, Mengmeng Li, Feng Ji, Jinliang Chen, Dongmei Zhang
Topics & Concepts
A549 cellWestern blotSTAT3Epithelial–mesenchymal transitionCarcinogenesisGene silencingSignal transductionCancer researchCell migrationChemistrySmall hairpin RNAMolecular biologyBiologyCell biologyCellDownregulation and upregulationCancerGene knockdownBiochemistryApoptosisGeneGeneticsGlycosylation and Glycoproteins ResearchCarbohydrate Chemistry and SynthesisGalectins and Cancer Biology