Preparation, Optimization, and Evaluation of Dolutegravir Nanosuspension: In Vitro and In Vivo Characterization
Monika Bhairam, Ravindra Kumar Pandey, Shiv Shankar Shukla, Bina Gidwani
Topics & Concepts
DolutegravirBioavailabilitySolubilityZeta potentialSonicationMaterials scienceDrugDispersityPulmonary surfactantIn vivoDifferential scanning calorimetryChromatographyPharmacologyNanoparticleNanotechnologyChemistryMedicineHuman immunodeficiency virus (HIV)Organic chemistryAntiretroviral therapyVirologyBiotechnologyThermodynamicsBiochemistryBiologyPhysicsPolymer chemistryViral loadHIV/AIDS drug development and treatmentDrug Solubulity and Delivery SystemsProtein purification and stability