Lipoprotein imitating nanoparticles: Lecithin coating binds ApoE and mediates non-lysosomal uptake leading to transcytosis over the blood-brain barrier
A Wunsch, Dennis Mulac, Klaus Langer
Topics & Concepts
TranscytosisBlood–brain barrierChemistryApolipoprotein EBiophysicsLipoproteinDrug delivery to the brainDrug deliveryLysosomeLecithinDrug carrierEndocytosisApolipoprotein BBiochemistryCholesterolCentral nervous systemBiologyReceptorEndocrinologyInternal medicineEnzymeOrganic chemistryMedicineDiseaseProtein Interaction Studies and Fluorescence AnalysisNanoparticle-Based Drug DeliveryGold and Silver Nanoparticles Synthesis and Applications