Are chilblain‐like acral skin lesions really indicative of COVID‐19? A prospective study and literature review

Alexandre Docampo‐Simón, María José Sánchez‐Pujol, Gloria Juan‐Carpena, Juan Carlos Palazón‐Cabanes, Eduardo Vergara‐de Caso, L. Berbegal, I. Poveda‐Montoyo, N. Pastor‐Tomás, Javier Mataix-Díaz, C. Terencio‐Alemany, Antonela Martínez-Torres, Julia Miralles‐Botella, Mar Blanes‐Martínez, Iris González‐Villanueva, Isabel Betlloch

2020Journal of the European Academy of Dermatology and Venereology64 citationsDOI Open Access PDF

Abstract

][4] However, our histological findings are reminiscent of the pauci-inflammatory thrombogenic vasculopathy that occurs seriously ill hospitalized COVID-19 patients with COVID-19. This thrombogenic vasculopathy is due to activation of the complement pathways and an associated procoagulant state. However, no cases of thrombotic vasculopathy have been reported to date in asymptomatic children or young adults with acral lesions.

Topics & Concepts

MedicineDermatologyCoronavirus disease 2019 (COVID-19)Context (archaeology)Prospective cohort studySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Pneumonia2019-20 coronavirus outbreakSurgeryPathologyDiseaseOutbreakInternal medicineBiologyInfectious disease (medical specialty)PaleontologyDermatological and COVID-19 studiesParvovirus B19 Infection StudiesStreptococcal Infections and Treatments