Reduced-Intensity/Reduced-Toxicity Conditioning Approaches Are Tolerated in XIAP Deficiency but Patients Fare Poorly with Acute GVHD
Danielle E. Arnold, Rofida Nofal, Connor Wakefield, Kai Lehmberg, Katharina Wustrau, Michael H. Albert, Emma Morris, Jennifer Heimall, Nancy Bunin, Ashish Kumar, Michael B. Jordan, Theresa Cole, Sharon Choo, Tim Brettig, Carsten Speckmann, Stephan Ehl, Małgorzata Salamonowicz, Justin T. Wahlstrom, Kanchan Rao, Claire Booth, Austen Worth, Rebecca Marsh
Topics & Concepts
MedicineInternal medicineHemophagocytic lymphohistiocytosisHazard ratioGastroenterologyRetrospective cohort studyHematopoietic stem cell transplantationXIAPTransplantationImmunologyDiseaseConfidence intervalBiochemistryProgrammed cell deathApoptosisCaspaseChemistryAutoimmune and Inflammatory Disorders ResearchHematopoietic Stem Cell TransplantationImmune Cell Function and Interaction