Structural basis for selectivity in a highly reducing type II polyketide synthase
Danyao Du, Yohei Katsuyama, Masanobu Horiuchi, Shinya Fushinobu, Aochiu Chen, Tony D. Davis, Michael D. Burkart, Yasuo Ohnishi
Topics & Concepts
Acyl carrier proteinPolyketidePolyketide synthaseStereochemistryChemistryPolyeneBiosynthesisMutagenesisEscherichia coliActive siteProtein structureEnzymeBiochemistryGeneMutationMicrobial Natural Products and BiosynthesisCarbohydrate Chemistry and SynthesisPlant-Microbe Interactions and Immunity