The kinase PDK1 regulates regulatory T cell survival via controlling redox homeostasis
Peiran Feng, Quanli Yang, Liang Luo, Yadong Sun, Wenkai Lv, Shuo Wan, Zerong Guan, Zhi‐Qiang Xiao, Feng Liu, Zehua Li, Zhongjun Dong, Meixiang Yang
Abstract
Our results defined a key finding on the mechanism by which PDK1 regulates Treg cell survival via controlling redox homeostasis.
Topics & Concepts
Cell biologyBiologyHomeostasisFOXP3MAPK/ERK pathwayKinaseProtein kinase AImmune systemImmunologyT-cell and B-cell ImmunologyImmune Cell Function and InteractionInvertebrate Immune Response Mechanisms