ATF4-mediated GDF15 suppresses LPS-induced inflammation and MUC5AC in human nasal epithelial cells through the PI3K/Akt pathway
An Li, Fangfang Zhao, Yuxiang Zhao, Hui Liu, Zhou Wang
Topics & Concepts
PI3K/AKT/mTOR pathwayInflammationGDF15Gene silencingProtein kinase BLY294002GCLCSecretionProinflammatory cytokineCell biologyCancer researchSignal transductionBiologyEndocrinologyInternal medicineImmunologyDownregulation and upregulationMedicineBiochemistryGeneGDF15 and Related BiomarkersIL-33, ST2, and ILC PathwaysClusterin in disease pathology