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Bazedoxifene inhibits PDGF-BB induced VSMC phenotypic switch via regulating the autophagy level

Wenmin Song, Kai Gao, Panhao Huang, Zizhao Tang, Fangqin Nie, Sujie Jia, Ren Guo

2020Life Sciences21 citationsDOI

Topics & Concepts

Platelet-derived growth factor receptorVascular smooth muscleProtein kinase BWestern blotViability assayAutophagyPlatelet-derived growth factorCell growthVimentinMAPK/ERK pathwayPharmacologyChemistryBiologyCancer researchCell biologyEndocrinologyGrowth factorInternal medicineSignal transductionMedicineReceptorCellImmunohistochemistryBiochemistryApoptosisSmooth muscleGeneAtherosclerosis and Cardiovascular DiseasesAdipokines, Inflammation, and Metabolic DiseasesCancer-related molecular mechanisms research
Bazedoxifene inhibits PDGF-BB induced VSMC phenotypic switch via regulating the autophagy level | Litcius