Litcius/Paper detail

mTORC1 regulates a lysosome-dependent adaptive shift in intracellular lipid species

Aaron M. Hosios, Meghan E. Wilkinson, Molly C. McNamara, Krystle C. Kalafut, Margaret E. Torrence, John M. Asara, Brendan D. Manning

2022Nature Metabolism53 citationsDOIOpen Access PDF

Topics & Concepts

LysosomemTORC1IntracellularCell biologyBiologyChemistryBiochemistrySignal transductionPI3K/AKT/mTOR pathwayEnzymeLipid metabolism and biosynthesisPI3K/AKT/mTOR signaling in cancerAutophagy in Disease and Therapy