GSH-activatable camptothecin prodrug-loaded gold nanostars coated with hyaluronic acid for targeted breast cancer therapy <i>via</i> multiple radiosensitization strategies
Yingke Hou, Bin Sun, Rongtian Li, Wei Meng, Wen‐Hua Zhang, Nuan Jia, Ming Chen, Jin-Xiang Chen, Xiao‐Yan Tang
Abstract
radiosensitizing therapy combined with PTT. This work provides a new way of constructing a structurally compact and highly functionalized hierarchical system toward efficient breast cancer treatment through ameliorating the TME with multiple modalities.
Topics & Concepts
RadiosensitizerProdrugCamptothecinChemistryTumor microenvironmentCancer researchGlutathioneBiophysicsBiochemistryRadiation therapyMedicineBiologyInternal medicineTumor cellsEnzymeNanoplatforms for cancer theranosticsNanoparticle-Based Drug DeliveryExtracellular vesicles in disease