Improved bioavailability and anticancer efficacy of Hesperetin on breast cancer via a self-assembled rebaudioside A nanomicelles system
Jun Wang, Qiqi Li, Zekun Chen, Xueju Qi, Xianggen Wu, Guohu Di, Junting Fan, Chuanlong Guo
Topics & Concepts
BioavailabilityChemistryMicellePI3K/AKT/mTOR pathwayHesperetinIn vivoPharmacologyReactive oxygen speciesCytotoxicityProtein kinase BApoptosisBiochemistryIn vitroAntioxidantBiologyAqueous solutionFlavonoidPhysical chemistryBiotechnologyNatural product bioactivities and synthesisFlavonoids in Medical ResearchPolysaccharides and Plant Cell Walls