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Design and development of Tetrahydro-Quinoline derivatives as dual mTOR-C1/C2 inhibitors for the treatment of lung cancer

Udit Chaube, Rakesh Rawal, Abhishek Jha, Bhavesh C. Variya, Hardik Bhatt

2020Bioorganic Chemistry24 citationsDOI

Topics & Concepts

mTORC2PI3K/AKT/mTOR pathwaymTORC1ChemistryLung cancerProtein kinase BCancer researchWestern blotPharmacophoreCancerPharmacologyBiochemistryBiologyPhosphorylationApoptosisMedicineOncologyGeneGeneticsPI3K/AKT/mTOR signaling in cancerFungal Plant Pathogen ControlLung Cancer Treatments and Mutations
Design and development of Tetrahydro-Quinoline derivatives as dual mTOR-C1/C2 inhibitors for the treatment of lung cancer | Litcius