Effects of dietary fiber on intestinal iron absorption, and physiological status: a systematic review of <i>in vivo</i> and clinical studies
Thaísa Agrizzi Verediano, Nikita Agarwal, Mariana Juste Contin Gomes, Hércia Stampini Duarte Martino, Elad Tako
Abstract
. The studies included assessment of dietary fiber in the form of fructo-oligosaccharides, galacto-oligosaccharides, inulin, pectin, guar gum, oligofructose, xylo-oligosaccharides, and mannan-oligosaccharide. Hemoglobin (n = 21) and fractional iron absorption (n = 6) were the most frequently reported outcomes. The results showed no significant correlations between consumption of dietary fiber to iron absorption/status-related biomarkers. However, the current evidence may not be substantial to invalidate the recommendation of dietary fiber as an agent to improve dietary iron bioavailability, and absorption. In conclusion, there is a need to conduct further clinical trials with long dietary fiber intervention focusing on population at high risk for iron deficiency.