Albiflorin, a Monoterpene Glycoside, Protects Myoblasts against Hydrogen Peroxide-Induced Apoptosis by Activating the Nrf2/HO-1 Axis
Cheol Park, Hee‐Jae Cha, Dong‐Gu Kim, Su Hyun Hong, Sung‐Kwon Moon, Cheng‐Yun Jin, Gi‐Young Kim, Heui‐Soo Kim, Na Yeong Lee, Jung‐Hyun Shim, Yung Hyun Choi
Abstract
-induced apoptosis and decreased cell viability. Taken together, these findings suggest that albiflorin protects myoblasts from oxidative stress-induced DNA damage and apoptosis by activating Nrf2/HO-1 signaling, thus highlighting its potential in the management of myofunctional homeostasis.
Topics & Concepts
ChemistryReactive oxygen speciesOxidative stressApoptosisDNA damageHydrogen peroxideAntioxidantBiochemistryDNAGenomics, phytochemicals, and oxidative stressTraditional Chinese Medicine AnalysisGinger and Zingiberaceae research