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Photo‐Induced Oxidative C−H Esterification of Quinoxalinones with Arylaldehydes under Mild Conditions

Kai Zheng, Chaoyang Wang, Yacong Wang, Chao Chen, Chao Shen

2025Advanced Synthesis & Catalysis24 citationsDOIOpen Access PDF

Abstract

Abstract The first example for photo‐induced oxidative C−H esterification of quinoxalinones with arylaldehydes under benign conditions has been reported. This method is distinguished by its capacity to accommodate a diverse array of quinoxalinones and arylaldehydes, culminating in the synthesis of the corresponding esters with moderate to good yields. The protocol is lauded for its environmental benignity, eschewing the need for hazardous transition metals and costly photocatalysts, and relies solely on hydrogen peroxide (H 2 O 2 ) as the oxidant. Moreover, the scalability of the synthesis and the derivative transformations of the products have been demonstrated, underscoring its practical utility in organic synthesis.

Topics & Concepts

ChemistryOxidative phosphorylationOrganic chemistryCombinatorial chemistryBiochemistrySynthesis and Biological Evaluation
Photo‐Induced Oxidative C−H Esterification of Quinoxalinones with Arylaldehydes under Mild Conditions | Litcius