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Serum exosomal m6A demethylase FTO promotes gefitinib resistance in non-small cell lung cancer by up-regulating FLRT3, PTGIS and SIRPα expression

Qi Wang, Lin Zhang, Zhenzhong Su, Wei Li, Yuxi Jia, Jie Zhang, Jie Zhang

2023Pulmonary Pharmacology & Therapeutics12 citationsDOI

Topics & Concepts

DemethylaseGefitinibGeneOncologyInternal medicineCancer researchmicroRNADownregulation and upregulationLung cancerMedicineBiologyCancerEpigeneticsEpidermal growth factor receptorGeneticsRNA modifications and cancerCancer-related molecular mechanisms researchFerroptosis and cancer prognosis
Serum exosomal m6A demethylase FTO promotes gefitinib resistance in non-small cell lung cancer by up-regulating FLRT3, PTGIS and SIRPα expression | Litcius