Pyrazole (1, 2-diazole) induce apoptosis in lymphoma cells by targeting BCL-2 and BCL-XL genes and mitigate murine solid tumour development by regulating cyclin-D1 and Ki-67 expression
Walsan Kalarikkal Vishnu, Prathapan Abeesh, Chandrasekharan Guruvayoorappan
Topics & Concepts
PyrazoleCyclin D1Cancer researchApoptosisBiologyCancer cellIn vitroPharmacologyProgrammed cell deathBcl-xLCancerChemistryBiochemistryCell cycleStereochemistryGeneticsCell death mechanisms and regulationCancer Mechanisms and TherapyComputational Drug Discovery Methods