Identification of potential N-substituted 5-benzylidenethiazolidine-2,4‑dione derivatives as α-amylase inhibitors: Computational cum synthetic studies
Shankar Gupta, Gurkaran Singh Baweja, Ghanshyam Das Gupta, Vivek Asati
Topics & Concepts
PharmacophoreChemistryIn silicoVirtual screeningEnzymeDocking (animal)AmylaseGlycosidic bondQuantitative structure–activity relationshipStereochemistryIC50Combinatorial chemistryComputational biologyBiochemistryIn vitroBiologyGeneMedicineNursingComputational Drug Discovery MethodsEnzyme Production and CharacterizationNatural Antidiabetic Agents Studies