Study on the Combined Toxicities and Quantitative Characterization of Toxicity Sensitivities of Three Flavor Chemicals and Their Mixtures to <i>Caenorhabditis elegans</i>

Abstract

. In mixture systems, the toxicity sensitivities of mixture rays with different mixture ratios were also different at different exposure volumes. In addition, it can be seen from the CI heat map that the toxicological interaction not only shows the mixture ratio dependence but also changes with the different exposure volumes, which implies that the mixtures consisting of flavor chemicals with high toxicity sensitivity have complex toxicological interactions. Therefore, in environmental risk assessment, special attention should be paid to chemicals with high toxicity sensitivities.

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