Desymmetrizing Isomerization of Alkene via Thiazolinyl Iminoquinoline Cobalt Catalysis
Wen‐Bo Liu, Yushan Zheng, Yihui Mao, Jieping Chen, Xiang Ren, Zhaoyang Cheng, Zhan Lu
Abstract
-cyclic alkenes to generate chiral 1-methylcyclohexene derivatives with good yields and enantioselectivities. A novel chiral thiazolinyl iminoquinoline ligand and its cobalt complex were designed and synthesized to control the establishment of tertiary or quaternary carbon centers at a remote position. This protocol is operationally simple, and a model for the stereochemical outcome has been proposed.
Topics & Concepts
IsomerizationChemistryCobaltAlkeneCatalysisLigand (biochemistry)Quaternary carbonCarbon fibersCombinatorial chemistryOrganic chemistryEnantioselective synthesisReceptorMaterials scienceComposite materialBiochemistryComposite numberCatalytic C–H Functionalization MethodsSynthetic Organic Chemistry MethodsAsymmetric Synthesis and Catalysis