Design, synthesis, docking, and antiviral evaluation of some novel pyrimidinone-based α-aminophosphonates as potent H1N1 and HCoV-229E inhibitors
Hend A. Hekal, Omar M. Hammad, Nasser R. El‐Brollosy, Maha M. Salem, Abdou Kamal Allayeh
Topics & Concepts
ChemistryPhosphonateNeuraminidaseDocking (animal)In vitroNeuraminidase inhibitorStereochemistryIn silicoInfluenza A virusVirusEnzymeBiochemistryVirologyCoronavirus disease 2019 (COVID-19)GeneNursingDiseasePathologyInfectious disease (medical specialty)BiologyMedicineSynthesis and biological activityPneumocystis jirovecii pneumonia detection and treatmentOrganophosphorus compounds synthesis