Litcius/Paper detail

Treatment of HCC with claudin-1-specific antibodies suppresses carcinogenic signaling and reprograms the tumor microenvironment

Natascha Roehlen, Marion Müller, Zeina Nehme, Émilie Crouchet, Frank Jühling, Fabio Del Zompo, Sara Cherradi, François H.T. Duong, Nuno Almeida, Antonio Saviano, Mirian Fernández-Vaquero, Tobias Riedl, Houssein El Saghire, Sarah Durand, Clara Ponsolles, Marine A. Oudot, Romain Martin, Nicolas Brignon, Emanuele Felli, Patrick Pessaux, Antonin Lallement, Irwin Davidson, Simonetta Bandiera, Christine Thumann, Patrice Marchand, Solange Moll, Brandon Nicolay, Nabeel Bardeesy, Yujin Hoshida, Mathias Heikenwälder, Roberto Iacone, Alberto Toso, Markus Meyer, Greg Elson, Tamás Schweighoffer, Geoffrey Teixeira, Mirjam B. Zeisel, Patrice Laquerrière, Joachim Lupberger, Catherine Schuster, Laurent Mailly, Thomas F. Baumert

2022Journal of Hepatology45 citationsDOIOpen Access PDF

Topics & Concepts

ClaudinCancer researchTumor microenvironmentTight junctionMonoclonal antibodyBiologyHepatocellular carcinomaCellMedicineAntibodyImmunologyCell biologyTumor cellsGeneticsBarrier Structure and Function StudiesSingle-cell and spatial transcriptomicsFerroptosis and cancer prognosis