BP5 alleviates endotoxemia-induced acute lung injury by activating Nrf2 via dual regulation of the Keap1-Nrf2 interaction and the Akt (Ser473)/GSK3β (Ser9)/Fyn pathway
Tianxiang Li, Zhirong Geng, Ju Zhang, Lu Xu, Xiaoli Zhu
Topics & Concepts
In vivoKEAP1ChemistryProtein kinase BPharmacologyFYNOxidative stressPhosphorylationInflammationIn vitroCell biologyCancer researchBiochemistryImmunologyMedicineBiologyProto-oncogene tyrosine-protein kinase SrcGeneTranscription factorBiotechnologyGenomics, phytochemicals, and oxidative stressIL-33, ST2, and ILC PathwaysImmune Response and Inflammation