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Flubendazole, FDA-approved anthelmintic, elicits valid antitumor effects by targeting P53 and promoting ferroptosis in castration-resistant prostate cancer

Xumin Zhou, Libin Zou, Wenbin Chen, Taowei Yang, Junqi Luo, Kaihui Wu, Fangpeng Shu, Xiao Tan, Yang Yu, Shengren Cen, Chuanyin Li, Xiangming Mao

2020Pharmacological Research97 citationsDOI

Topics & Concepts

Prostate cancerDU145PharmacologyCell growthApoptosisCell cycleCancer researchMedicineCancerBiologyInternal medicineLNCaPGeneticsBiochemistryFerroptosis and cancer prognosisProstate Cancer Treatment and ResearchCancer, Lipids, and Metabolism
Flubendazole, FDA-approved anthelmintic, elicits valid antitumor effects by targeting P53 and promoting ferroptosis in castration-resistant prostate cancer | Litcius