Arrhythmic causes of in-hospital cardiac arrest among patients with heart failure with preserved ejection fraction
Matthew Hooks, Michael C. Downey, Stephanie Joppa, Albertine Beard, Amy Gravely, Venkat Tholakanahalli, Selçuk Adabağ
Abstract
More than half of all heart failure (HF) cases in the United States are due to HF with preserved ejection fraction (HFpEF), which has no medical treatments proven to reduce its mortality rate.1 Sudden cardiac death (SCD) comprises ∼25% of all deaths in HFpEF, and may be a potential therapeutic target.2 However, whether the SCD in HFpEF is due to ventricular tachycardia (VT) or ventricular fibrillation (VF), amenable to termination by implantable cardioverter-defibrillator (ICD) therapy, is unclear.
Topics & Concepts
MedicineCardiologyInternal medicineEjection fractionVentricular fibrillationImplantable cardioverter-defibrillatorHeart failureVentricular tachycardiaSudden cardiac deathTachycardiaCardiac pacing and defibrillation studiesCardiac electrophysiology and arrhythmiasCardiovascular Function and Risk Factors