Samarium Diiodide/Samarium-Mediated Deoxygenative Hydrosilylation of Ketones
Ruxing Li, Yilin Ma, Jianwen Zhang, Chengwei Liu
Abstract
The first deoxygenative hydrosilylation of ketones promoted by samarium diiodide and samarium has been reported. In this approach, secondary alkyl silanes are synthesized from unactivated ketones and chlorosilanes in one step. The carbonyl group of ketones is activated by SmI 2 -mediated single-electron transfer process, which follows a deoxygenative elimination of O=Sm. Broad substrate scope and excellent functional group tolerance has been demonstrated.
Topics & Concepts
HydrosilylationSamariumSilanesAlkylSamarium diiodideChemistrySubstrate (aquarium)KetoneOrganic chemistryMedicinal chemistryCatalysisBiologySilaneEcologyOrganoboron and organosilicon chemistryCatalytic C–H Functionalization MethodsChemical Synthesis and Analysis