Litcius/Paper detail

Impact of body mass index on outcomes in patients undergoing transfemoral transcatheter aortic valve implantation

Astrid van Nieuwkerk, Raquel B. Santos, Samantha Sartori, Ander Regueiro, Didier Tchétché, Roxana Mehran, Ronak Delewi, Flavio S. De Brito, Flávio Tarasoutchi, Marco Barbanti, Ran Kornowski, Katia Orvin, Azeem Latib, Matteo Pagnesi, Augusto D’Onofrio, Giuseppe Tarantini, Flavio Ribichini, Mattia Lunardi, Jan Baan, Jan G.P. Tijssen, José P.S. Henriques, Francisco Ten, Nicolas Dumonteil, Angie Ghattas, Paola D’Errigo, Juan Manuel Nogales‐Asensio, Thomas Modine, George Dangas

2021JTCVS Open17 citationsDOIOpen Access PDF

Abstract

Objective: This study sought to investigate the effect of body mass index on outcomes in patients with severe aortic valve stenosis undergoing transcatheter aortic valve implantation. Methods: ). Primary endpoints were differences in 30-day and 1-year all-cause mortality. Secondary endpoints included all other clinical endpoints such as stroke. Univariate and multivariate odds ratios were calculated using logistic and cox regression analyses. Results: = .011). Stroke rates were comparable between body mass index groups. Conclusions: For overweight and obese patients with severe aortic valve stenosis undergoing transcatheter aortic valve implantation, there was no 30-day difference in mortality compared with patients with normal weight. However, underweight patients showed higher rates of 1-year mortality after transcatheter aortic valve implantation.

Topics & Concepts

MedicineUnderweightOdds ratioBody mass indexConfidence intervalOverweightHazard ratioInternal medicineCardiologyAortic valve stenosisAortic valveSurgeryCardiac Valve Diseases and TreatmentsCardiovascular Function and Risk FactorsCardiovascular Health and Disease Prevention