Injectable hydrogels in stroke and spinal cord injury treatment: a review on hydrogel materials, cell–matrix interactions and glial involvement
Po Hen Lin, Quanbin Dong, Sing Yian Chew
Abstract
Cell–matrix interactions and glia involvement are crucial factors to be considered for the design of injectable hydrogels in the treatment of central nervous system pathologies.
Topics & Concepts
Self-healing hydrogelsSpinal cord injuryMedicineMatrix (chemical analysis)Stroke (engine)Spinal cordCentral nervous systemMaterials scienceInternal medicineEngineeringMechanical engineeringPolymer chemistryPsychiatryComposite materialNerve injury and regenerationNeurogenesis and neuroplasticity mechanismsSpinal Cord Injury Research